Tag: Synthetic Biology2

Impact Companies Tag: Synthetic Biology 2

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Lygos target products are the specialty chemicals of today that can grow into the commodity chemicals of tomorrow. The primary hurdles restricting the market growth of these chemicals is their current high production cost or environmentally hazardous production process. Lygos address both these problems using a low cost microbial fermentation technology enabling over $25B in downstream value to be unlocked using their technology. Lygos make their products using commercially proven acid tolerant yeast. They have developed a suite of high throughput engineering technologies that enable us to rapidly prototype and optimize their microbes enabling low cost rapid technology scaleup.Many of their target products are organic acids compounds that are expensive to synthesize using petrochemistry but can be produced at high theoretical yield microbially. A high yielding process means less sugar is required to produce each kilogram of product decreasing operating costs and lowering exposure to changing raw material (e.g. corn) prices. For some compounds a theoretical yield greater than 100% can be achieved by sinking carbon dioxide. Low operating costs is a fundamental reason why microbial production of organic acids (e.g. itaconic lactic citric and succinic acids) has been more successful than biofuels (e.g. farnesane bio diesel butanol and ethanol).



Twist Biosciences

United States of America

Twist Bioscience Corp. was incorporated in 2013 and is based in San Francisco California. The Twist Bioscience platform has the potential to greatly accelerate the development of personalized medicine sustainable chemical production improved agriculture production as well as new applications such as in vivo diagnostics biodetection and data storage.